Wesley R Legant, PhD

September 18, 2018

Wesley R Legant, PhD

Joint Assistant Professor of Biomedical Engineering and Pharmacology

Resource Faculty
Phone: (919) 966-4816 | Office: 4047 Genetic Medicine Building
Email: legantw@email.unc.edu | Website: https://www.med.unc.edu/pharm/people/primaryfaculty/wesley-r-legant/wesley-r-legant

Research Areas: Computational Biophysics, Image Analysis
Research Interests: Microscopy, 3D image analysis, biomaterials, cell migration, cancer metastasis, tissue engineering


Daniel Dominguez, PhD

September 17, 2018

Daniel Dominguez, PhD

Assistant Professor of Pharmacology

Resource Faculty
Phone: (919) 966-0131 | Office: 4113 Genetic Medicine Building
Email: didoming@email.unc.edu | Website: https://dominguez-lab.org/

Research Areas: Bioinformatics, Comparative Genomics and Molecular Evolution, Computational Genomics, Computational Systems Biology
Research Interests: The Dominguez lab studies how gene expression is controlled by proteins that bind RNA. We apply high-throughput biochemical and computational approaches to understand protein-RNA interactions, RNA processing, and gene regulation in normal and disease biology.


Brian Strahl, PhD

August 31, 2018

Brian Strahl, PhD

Professor and Vice-Chair of Biochemistry & Biophysics

Resource Faculty
Phone: (919) 843-3896 | Office: 3060 Genetic Medicine
Email: brian_strahl@med.unc.edu | Website: http://www.med.unc.edu/~bstrahl/

Research Areas: Bioinformatics, Computational Biophysics, Computational Genomics
Research Interests: Our lab is interested in the role that histone post-translational modifications have in chromatin biology. Specifically, we are studying how enzymes that ‘write’ and ‘read’ histone modifications contribute to the function of chromatin and DNA-templated functions like gene transcription. To do so, we are employing a range of model organisms (yeast to mammalian cells) and approaches (genomics, genetics, biochemistry, biophysics as well as proteomics) that, together, are elucidating how readers and writer enzymes function to sculpt the chromatin landscape and regulate gene transcription. Students who join our lab would be involved in multiple UNC collaborations (as well as have individual projects) that would provide wide exposure these model systems and techniques.


C Ryan Miller, MD, PhD

August 30, 2018

C Ryan Miller, MD, PhD

Associate Professor of Pathology and Laboratory Medicine

Resource Faculty
Phone: (919) 966-4333 | Office: 6109B Neurosciences Research Building
Email: rmiller@med.unc.edu | Website: https://www.med.unc.edu/pathology/millerlab/

Research Areas: Bioinformatics, Computational Genomics
Research Interests: Development of novel mouse models of brain cancers and their comparative epigenomic, genomic, transcriptomic, and proteomic characterization relative to human tumors


Daniel Schrider, PhD

August 30, 2018

Daniel Schrider, PhD

Assistant Professor of Genetics

Core Faculty
Phone: (919) 843-6475 | Office: 5111 Genetic Medicine Building
Email: dschride@email.unc.edu | Website: https://www.schriderlab.org/

Research Areas: Bioinformatics, Comparative Genomics and Molecular Evolution, Computational Genomics, Statistical and Population Genetics
Research Interests: We develop and apply computational tools to make inferences about evolution from population genomic datasets. Our research areas include the population genetics of adaptation, genomic copy number variants, and the application of supervised machine learning tools to evolutionary questions.


Cavin Ward-Caviness, PhD

August 30, 2018

Cavin Ward-Caviness, PhD

Computational Biologist/Principal Investigator of US EPA

Core Faculty
Phone: (919) 966-5445 | Office: 104 Mason Farm Road
Email: ward-caviness.cavin@epa.gov | Website: https://www.wc-lab.com/

Research Areas: Computational Genomics, Statistical and Population Genetics
Research Interests: My primary research interest is in using large clinical databases to uncover environmental and social health risks. In addition I am interested in furthering the use of machine learning in environmental epidemiology and uncovering molecular biomarkers for environmental health risk and the molecular mechanisms by which environmental exposures are translated into health outcomes.