Daniel Dominguez, PhD

September 17, 2018

Daniel Dominguez, PhD

Assistant Professor of Pharmacology

Resource Faculty
Phone: (919) 966-0131 | Office: 4113 Genetic Medicine Building
Email: didoming@email.unc.edu | Website: https://dominguez-lab.org/

Research Areas: Bioinformatics, Comparative Genomics and Molecular Evolution, Computational Genomics, Computational Systems Biology
Research Interests: The Dominguez lab studies how gene expression is controlled by proteins that bind RNA. We apply high-throughput biochemical and computational approaches to understand protein-RNA interactions, RNA processing, and gene regulation in normal and disease biology.


Shehzad Sheikh, MD, PhD

August 30, 2018

Shehzad Sheikh, MD, PhD

Associate Professor of Genetics and Medicine

Resource Faculty
Phone: (919) 966-0745 | Office: 7320 Medical Biomolecular Research Building
Email: sheisx@med.unc.edu | Website: http://sheikhlab.web.unc.edu/

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: We seek to understand how information is encoded and dynamically utilized in immune cells from healthy and disease prone intestines (Crohn’s disease and Ulcerative colitis). We focus specifically on genes that regulate response to the bacteria that normally reside in our intestines. We use genome-sequencing technology to precisely identify regions throughout the genome that are potential ‘on’ or ‘off’ switches for these genes.


Katherine A. Hoadley, PhD

August 21, 2018

Katherine Hoadley, PhD

Assistant Professor of Genetics

Resource Faculty
Phone: (919) 962-8416 | Office: 5212 Marsico Hall
Email: hoadley@med.unc.edu | Website: https://unclineberger.org/people/profiles/katherine-hoadley

Research Areas: Computational Genomics, Bioinformatics, Computational Systems Biology
Research Interests: My research interest is in genomic characterization and integrative genomic approaches to better understand cancer. My group is part of the NCI Genome Data Analysis Center focused on RNA expression analysis. We have a number of ongoing projects including developing molecular classifications for potential clinical utility, developing methods for deconvolution to understand bulk tissue heterogeneity, analysis of driver negative cancers, and analysis of ancestry markers with cancer features.


Hector Franco

June 5, 2018

Hector L Franco, PhD

Assistant Professor of Genetics; UNC Lineberger Cancer Center

Resource Faculty
Phone: (919) 966-5269 | Office: 5109 Marsico Hall
Email: hfranco@med.unc.edu | Website: https://www.thefrancolab.org/

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: The Franco lab has a long-standing interest in gene regulation, epigenetics, chromatin and RNA biology, especially as it pertains to cancer. We address these research aims by using an interdisciplinary approach that combines molecular and cellular techniques with functional genomic and computational approaches.


Doug Phanstiel, PhD

February 9, 2018

Doug Phanstiel, PhD

Assistant Professor of Cell Biology & Physiology

Resource Faculty
Phone: 919-843-8847 | Office: 4019 Thurston Bowles Building
Email: douglas_phanstiel@med.unc.edu | Website: http://www.unc.edu/~dphansti/

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: We employ experimental and computational approaches to study the mechanisms through which enhancers and three-dimensional chromatin structure regulate gene transcription during cellular differentiation. The goals of our computational work include improved detection and quantification of three-dimensional chromatin structures and new tools for visualizing multi-dimensional genomic data.


Di Wu

November 17, 2016

Di Wu, PhD

Assistant Professor of Periodontics, School of Dentistry; Biostatistics

Resource Faculty
Phone: 919-537-3277 | Office: 4504 Koury Oral Health Sciences Building
Email: dwu@unc.edu | Website: http://sph.unc.edu/adv_profile/di-wu-phd/

Research Areas: Bioinformatics, Computational Genomics, Computational System Biology, Statistical and Population Genetics​
Research Interests: Development of statistical methods for multidimensional genomic data integration to understand the biological mechanism of diseases.


Benjamin Vincent, MD

March 31, 2016

Benjamin Vincent, MD

Assistant Professor of Medicine, Division of Hematology/Oncology

Resource Faculty
Phone: 919-962-8412 | Office: 5206 Marsico Hall
Email: bgvincen@unch.unc.edu | Website:

Research Areas: Computational Immunology, Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: Current research focuses on how immunogenomics features including T cell receptor and B cell receptor repertoire characteristics predict survival and response to immunotherapy in breast cancer, bladder cancer, and acute myeloid leukemia.


Jason Stein, PhD

March 17, 2016

Jason Stein, PhD

Assistant Professor of Genetics

Core Faculty
Phone: (919) 843-5541 | Office: 8109C Neuroscience Research Bldg.
Email: jason_stein@med.unc.edu | Website: http://www.steinlab.org/

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: The focus of our research is finding and modeling genetic variants influencing human brain structure and function.


Ben Major, PhD

February 25, 2016

Ben Major, PhD

Assistant Professor of Cell Biology and Physiology; Lineberger Comprehensive Cancer Center

Resource Faculty
Phone: 919-259-2695 | Office: Lineberger Comprehensive Cancer Center, Room 31-322
Email: benmajor@med.unc.edu | Website: http://cancer.unc.edu/majorlab/research.php

Research Areas: Bioinformatics, Computational Systems Biology
Research Interests: Computational proteomics and mass spectrometry. Network structure and dynamics of protein-protein interactions. Multi-OMIC integrations focused on signal transduction in cancer initiation and evolution.