John Sondek, PhD

July 20, 2015

John Sondek, PhD

Professor of Pharmacology, and Biochemistry & Biophysics

Resource Faculty
Phone: 919-966-7530 | Office: 4060 Genetic Medicine Bldg.
Email: sondek@med.unc.edu | Website: http://www.med.unc.edu/pharm/sondeklab

Research Areas: Bioinformatics, Computational Biophysics, Computational Systems Biology
Research Interests: Signaling networks controlled by GTPases; structural biology; chemical biology; biosensors design and use; cancer therapeutics


Mark Zylka, PhD

July 8, 2015

Mark Zylka, PhD

Associate Professor of UNC Neuroscience Center, Dept. of Cell Biology & Physiology

Resource Faculty
Phone: 919-966-2540 | Office: 5109 D Neuroscience Research Building
Email: zylka@med.unc.edu | Website: https://www.med.unc.edu/cellbiophysio/faculty/zylka

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology, Image Analysis
Research Interests: Use of genome-wide approaches to study transcriptional regulators linked to autism; Use of RNA-seq and targeted sequencing to identify chemical risk factors for brain disorders (autism, brain aging, neurodegeneration, ADHD); Transcriptional mechanisms associated with long genes


Charles M. Perou, PhD

July 8, 2015

Charles M. Perou, PhD

The May Goldman Shaw Distinguished Professor of Molecular Oncology, of Genetics and Pathology & Laboratory Medicine

Core Faculty
Phone: 919-843-5740 | Office: 5111 Marsico Hall
Email: cperou@med.unc.edu | Website: http://peroulab.med.unc.edu/

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: The focus of the Perou Lab is to characterize the biological diversity of human tumors using genomics, genetics, and cell biology, and to then use this information to develop computational predictors of tumor responsiveness and patient outcomes. We use a variety of genomic data types including RNA-seq, DNA exomes/WGS, and DNA copy number data to build these objective models. A major focus of the lab is on novel algorithm development, and the translation of these genomic predictors into clinical assays for use on cancer patients.


Laura Miller, PhD

June 25, 2015

Laura Miller, PhD

Associate Professor of Mathematics and Biology

Core Faculty
Phone: 919-843-4557 | Office: G44 Wilson
Email: Lam9@unc.edu | Website: https://miller.web.unc.edu/

Research Areas: Computational Biophysics, Computational Systems Biology
Research Interests: Biomechanics, mathematical biology


Shawn Gomez, Eng.Sc.D

June 25, 2015

Shawn Gomez, Eng.Sc.D

Associate Professor of Joint Department of Biomedical Engineering at UNC-Chapel Hill and NC State University

Core Faculty
Phone: 919-966-4959 | Office: 144 MacNider Hall
Email: smgomez@unc.edu | Website: http://gomezlab.bme.unc.edu/

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology, Image Analysis
Research Interests: Systems biology with emphases in cancer and infectious disease


Jeff Dangl, PhD

June 25, 2015

Jeff Dangl, PhD

HHMI Investigator and John N. Couch Professor of Biology

Core Faculty
Phone: 919-962-4469 | Office: 4260 Genome Sciences Bldg.
Email: dangl@email.unc.edu | Website: http://labs.bio.unc.edu/dangl/

Research Areas: Comparative Genomics and Molecular Evolution, Computational Genomics, Computational Systems Biology, Statistical and Populational Genetics
Research Interests: Plant Immune System, Plant Microbiome research


Peter J. Mucha, PhD

June 25, 2015

Peter J. Mucha, PhD

Bowman and Gordon Gray Distinguished Term Professor of Mathematics

Resource Faculty
Phone: 919-962-1294 | Office: 425 Chapman Hall
Email: mucha@unc.edu | Website: http://mucha.web.unc.edu/

Research Areas: Bioinformatics, Computational Systems Biology
Research Interests: Applied & Computational Mathematics, Networks, Complex Systems, Data Science


Jeremy Purvis, PhD

June 25, 2015

Jeremy Purvis, PhD

Assistant Professor of Genetics

Core Faculty
Phone: 919-962-4923 | Office: 5061 Genetic Medicine Bldg.
Email: jeremy_purvis@med.unc.edu | Website: http://genetics.unc.edu/purvislab/

Research Areas: Bioinformatics, Computational Systems Biology, Image Analysis
Research Interests: Our lab uses computational and experimental approaches to study signaling mechanisms in stem cells and cancer pathways. We are especially interested in understanding the molecular mechanisms underlying “irreversible” cell fate decisions such as apoptosis, senescence, and differentiation. We study the timing and mechanism of these decisions using a combination of time-lapse microscopy and computational modeling. Our ultimate goal is to not only understand how cells make decisions under physiological conditions, but to discover how to manipulate these decisions to treat disease.


Klaus Hahn, PhD

June 25, 2015

Klaus Hahn, PhD

Distinguished Professor of Pharmacology and Medicinal Chemistry

Resource Faculty
Phone: 919-843-2775 | Office: 4043 Genetic Medicine Bldg.
Email: khahn@med.unc.edu | Website: http://www.hahnlab.com

Research Areas: Computational Biophysics, Computational Systems Biology, Image Analysis
Research Interests: visualization and control of protein function in living cells and animals, using protein engineering and small molecule synthesis; signaling dynamics; motility, megakaryocyte and immune cell function