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Meredith Corley (graduate student, Laederach Lab) is first author on a paper published last week in Nucleic Acids Research that was titled: “Detecting riboSNitches with RNA folding algorithms: a genome-wide benchmark”. In the paper, Meredith and collaborators evaluate 11 different RNA folding algorithms’ riboSNitch prediction performance from a recently published human genome-wide parallel analysis of RNA structure (PARS) study. This study establishes best practices for predicting how SNVs (Single Nucleotide Variants) will affect transcriptome structure and builds on a growing body of evidence suggesting RNA structure is a key component of cellular regulation. See student pubs page for complete citation.

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