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Jan F. Prins, PhD

July 13, 2015

Jan F. Prins, PhD

Professor of Computer Science

Core Faculty
Phone: 919-590-6213 | Office: FB334 Brooks Computer Science Building
Email: prins@cs.unc.edu | Website: http://www.cs.unc.edu/~prins/

Research Areas: Bioinformatics, Computational Biophysics, Computational Genomics
Research Interests: RNA sequencing and analysis; Parallel Computing


Flavio Frohlich, PhD

July 8, 2015

Flavio Frohlich, PhD

Assistant Professor of Psychiatry, Cell Biology and Physiology, Biomedical Engineering, Neurology

Core Faculty
Phone: 919-966-4584 | Office: 4109F Neurosciences Research Bldg.
Email: flavio_frohlich@med.unc.edu | Website: http://www.frohlichlab.org

Research Areas: Computational Biophysics
Research Interests: Our goal is to revolutionize the treatment of psychiatric and neurological illness by developing novel brain stimulation paradigms. We identify and target network dynamics of physiological and pathological brain function. We combine computational modeling, optogenetics, in vitro and in vivo electrophysiology in animal models and humans, control engineering, and clinical trials. We strive to make our laboratory a productive, collaborative, and happy workplace.


Mark Zylka, PhD

July 8, 2015

Mark Zylka, PhD

Professor of UNC Neuroscience Center, Dept. of Cell Biology & Physiology

Resource Faculty
Phone: 919-966-2540 | Office: 5109 D Neuroscience Research Building
Email: zylka@med.unc.edu | Website: https://www.med.unc.edu/cellbiophysio/faculty/zylka

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology, Image Analysis
Research Interests: Use of genome-wide approaches to study transcriptional regulators linked to autism; Use of RNA-seq and targeted sequencing to identify chemical risk factors for brain disorders (autism, brain aging, neurodegeneration, ADHD); Transcriptional mechanisms associated with long genes


Amy Shaub Maddox, PhD

July 8, 2015

Amy Shaub Maddox, PhD

Associate Professor of Biology

Resource Faculty
Phone: 919-843-3228 | Office: 407 Fordham Hall
Email: asm@unc.edu | Website: http://asmlab.web.unc.edu

Research Areas: Computational Biophysics, Image Analysis
Research Interests: Molecular and mechanical mechanisms of cell shape changes in cell division and development


Boyce E. Griffith, PhD

July 8, 2015

Boyce E. Griffith, PhD

Associate Professor of Mathematics and Adjunct Assistant Professor of Biomedical Engineering

Core Faculty
Phone: 919-962-7110 | Office: 306 Phillips Hall
Email: boyceg@email.unc.edu | Website: http://griffith.web.unc.edu

Research Areas: Computational Biophysics
Research Interests: Mathematical modeling and computer simulation in physiology, especially cardiovascular mechanics, fluid dynamics, and fluid-structure interaction and cardiac electrophysiology.


Kerry Bloom, PhD

July 8, 2015

Kerry Bloom, PhD

Distinguished Professor of Biology

Resource Faculty
Phone: 919-962-1182 | Office: 623 Fordham Hall
Email: Kerry_bloom@unc.edu | Website: http://labs.bio.unc.edu/Bloom/

Research Areas: Computational Biophysics, Image Analysis
Research Interests: Chromosome dynamics in living cells


Daniel J. McKay, PhD

July 8, 2015

Daniel J. McKay, PhD

Associate Professor of Biology and Genetics

Resource Faculty
Phone: 919-843-2064 | Office: 3358 Genome Sciences Bldg.
Email: dmckay1@email.unc.edu | Website: http://mckaylab.web.unc.edu

Research Areas: Bioinformatics, Computational Genomics
Research Interests: Genetic and epigenetic regulation of gene expression during development


Charles M. Perou, PhD

July 8, 2015

Charles M. Perou, PhD

The May Goldman Shaw Distinguished Professor of Molecular Oncology, of Genetics and Pathology & Laboratory Medicine

Core Faculty
Phone: 919-843-5740 | Office: 5111 Marsico Hall
Email: cperou@med.unc.edu | Website: http://peroulab.med.unc.edu/

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: The focus of the Perou Lab is to characterize the biological diversity of human tumors using genomics, genetics, and cell biology, and to then use this information to develop computational predictors of tumor responsiveness and patient outcomes. We use a variety of genomic data types including RNA-seq, DNA exomes/WGS, and DNA copy number data to build these objective models. A major focus of the lab is on novel algorithm development, and the translation of these genomic predictors into clinical assays for use on cancer patients.


Fernando Pardo-Manuel de Villena, PhD

June 25, 2015

Fernando Pardo-Manuel de Villena, PhD

Oliver Smithies Investigator, Professor and Associate Chair of Genetics

Core Faculty
Phone: 919-843-5403 | Office: 5046 Genetic Medicine Bldg.
Email: fernando@med.unc.edu | Website:

Research Areas: Computational Genomics
Research Interests: Our research program lies in the interface between complex traits, evolutionary genetics and computational genomics