Katherine A. Hoadley, PhD
Katherine Hoadley, PhD
Associate Professor of
Genetics
Core Faculty
Phone: (919) 962-8416 | Office: 11-212 Mary Ellen Jones Building
Email: hoadley@med.unc.edu | Website: https://unclineberger.org/people/profiles/katherine-hoadley
Research Areas: Computational Genomics, Bioinformatics, Computational Systems Biology
Research Interests: My research interest is in genomic characterization and integrative genomic approaches to better understand cancer. My group is part of the NCI Genome Data Analysis Center focused on RNA expression analysis. We have a number of ongoing projects including developing molecular classifications for potential clinical utility, developing methods for deconvolution to understand bulk tissue heterogeneity, analysis of driver negative cancers, and analysis of ancestry markers with cancer features.
Hyejung Won
Hyejung Won, PhD
Assistant Professor of
Department of Genetics
Core Faculty
Phone: (919) 966-4069 | Office: 7202B Mary Ellen Jones Building, 116 Manning Dr.
Email: hyejung_won@med.unc.edu | Website: http://www.wonlab.org/
Research Areas: Bioinformatics, Statistical and Population Genetics
Research Interests: We try to bridge the gap between genetic risk factors for psychiatric illnesses and neurobiological mechanisms by decoding the regulatory relationships in human brain. In particular, we implement Hi-C, a genome-wide chromosome conformation capture technique, to identify the folding principle of the genome in human brain. We then leverage this information to identify the functional impacts of the common variants associated with neuropsychiatric disorders.
Doug Phanstiel, PhD
Doug Phanstiel, PhD
Assistant Professor of
Cell Biology & Physiology
Core Faculty
Phone: 919-843-8847 | Office: 4019 Thurston Bowles Building
Email: douglas_phanstiel@med.unc.edu | Website: http://www.unc.edu/~dphansti/
Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: We employ experimental and computational approaches to study the mechanisms through which enhancers and three-dimensional chromatin structure regulate gene transcription during cellular differentiation. The goals of our computational work include improved detection and quantification of three-dimensional chromatin structures and new tools for visualizing multi-dimensional genomic data.
Jill Dowen
Jill Dowen, PhD
Associate Professor of
Biochemistry & Biophysics and Biology
Resource Faculty
Phone: 919-962-8132 | Office: 3360 Genome Sciences Building
Email: jilldowen@unc.edu | Website: http://jilldowenlab.web.unc.edu/
Research Areas: Bioinformatics, Computational Genomics, Chromosome Conformation
Research Interests: Our research program integrates the areas of transcriptional regulation, three-dimensional genome organization and functional genomics to understand how the architecture of the genome influences gene expression during development and disease.
Michael Love
Michael Love, PhD
Associate Professor of
Genetics and Biostatistics
Core Faculty
Phone: (919) 966-7266 | Office: 5009 GMB
Email: milove@email.unc.edu | Website: https://mikelove.github.io
Research Areas: Bioinformatics, Computational Genomics, Statistical and Populational Genetics
Research Interests: The Love lab develops statistical and computational methods for the analysis of high-dimensional genomic data for biomedical and biological research. The Love lab has developed a number of open source software packages for the analysis of genomic datasets in R/Bioconductor.
Joel Parker
Joel Parker, PhD
Adjunct Associate Professor of
Genetics
Core Faculty
Phone: (919) 966-9614 | Office: 450 West Drive
Email: parkerjs@email.unc.edu | Website: https://lbc.unc.edu/
Research Areas: Bioinformatics, Computational Genomics
Research Interests: My research is focused in the methodological development and integrated analysis of high throughput genetic and genomic studies of cancer. Through the Lineberger Bioinformatics Shared Resource, we provide consultation and analytical services primarily for the Cancer Center, but are involved in collaborations across multiple departments and external institutions.
Jim Bear
Jim Bear, PhD
Professor of
Cell Biology and Physiology
Resource Faculty
Phone: (919) 966-5471 | Office: 21-223 Lineberger Comprehensive Cancer Center
Email: jbear@email.unc.edu | Website: https://www.med.unc.edu/cellbiophysio/people/primary-faculty/james-bear-phd
Research Areas:
Research Interests:
Di Wu
Di Wu, PhD
Associate Professor of
Periodontics, School of Dentistry; Biostatistics
Core Faculty
Phone: 919-537-3277 | Office: 4504 Koury Oral Health Sciences Building
Email: dwu@unc.edu | Website: http://sph.unc.edu/adv_profile/di-wu-phd/
Research Areas: Bioinformatics, Computational Genomics, Computational System Biology, Statistical and Population Genetics​
Research Interests: Development of statistical methods for multidimensional genomic data integration to understand the biological mechanism of diseases.
Benjamin Vincent, MD
Benjamin Vincent, MD
Associate Professor of
Medicine, Division of Hematology/Oncology
Resource Faculty
Phone: 919-962-8412 | Office: 5206 Marsico Hall
Email: bgvincen@unch.unc.edu | Website:
Research Areas: Computational Immunology, Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: Current research focuses on how immunogenomics features including T cell receptor and B cell receptor repertoire characteristics predict survival and response to immunotherapy in breast cancer, bladder cancer, and acute myeloid leukemia.
Jason Stein, PhD
Jason Stein, PhD
Associate Professor of
Genetics & Neuroscience Research Center
Core Faculty
Phone: (919) 843-5541 | Office: 7202A Mary Ellen Jones Building
Email: jason_stein@med.unc.edu | Website: http://www.steinlab.org/
Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: The focus of our research is finding and modeling genetic variants influencing human brain structure and function.