Karen Mohlke, PhDResource Faculty
Phone: 919-966-2913 | Office: 5096 Genetic Medicine Bldg.
Email: mohlke@med.unc.edu | Website: http://mohlke.web.unc.edu/
Research Areas: Bioinformatics, Computational Genomics, Statistical and Population Genetics
Research Interests: Genetic basis of complex metabolic traits
Jeremy Purvis, PhDCore Faculty
Phone: 919-962-4923 | Office: 11018C Mary Ellen Jones Building
Email: jeremy_purvis@med.unc.edu | Website: http://genetics.unc.edu/purvislab/
Research Areas: Bioinformatics, Computational Systems Biology, Image Analysis
Research Interests: Our lab uses computational and experimental approaches to study signaling mechanisms in stem cells and cancer pathways. We are especially interested in understanding the molecular mechanisms underlying “irreversible” cell fate decisions such as apoptosis, senescence, and differentiation. We study the timing and mechanism of these decisions using a combination of time-lapse microscopy and computational modeling. Our ultimate goal is to not only understand how cells make decisions under physiological conditions, but to discover how to manipulate these decisions to treat disease.
Kevin M. Weeks, PhDResource Faculty
Phone: 919-962-7486 | Office: 3258 Genome Sciences Building
Email: weeks@unc.edu | Website: http://www.chem.unc.edu/rna/
Research Areas: Bioinformatics, Computational Biophysics, Computational Genomics
Research Interests: Chemical Biology, Structural Biology, and Bioinformatics of the Transcriptome
J. Mauro Calabrese, PhDResource Faculty
Phone: 919-843-3257 | Office: 4093 Genetic Medicine Building
Email: jmcalabr@med.unc.edu | Website: http://www.med.unc.edu/pharm/calabreselab
Research Areas: Bioinformatics, Comparative Genomics and Molecular Evolution, Computational Genomics
Research Interests: Sequence rules to predict long noncoding RNA function, mechanisms of transcriptional regulation by long noncoding RNAs
