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Image Analysis

Kerry Bloom, PhD

Distinguished Professor of Biology

Resource Faculty
Phone: 919-962-1182 | Office: 623 Fordham Hall
Email: Kerry_bloom@unc.edu | Website: http://labs.bio.unc.edu/Bloom/

Research Areas: Computational Biophysics, Image Analysis
Research Interests: Chromosome dynamics in living cells

Timothy Elston, PhD

Professor of Pharmacology

Core Faculty
Phone: 919-843-7670 | Office: 4092 Genetic Medicine Bldg.
Email: telston@med.unc.edu | Website: http://www.med.unc.edu/pharm/elstonlab/

Research Areas: Computational Biophysics, Computational Systems Biology, Image Analysis
Research Interests: Mathematical modeling of signaling pathways and regulatory networks

Shawn Gomez, Eng.Sc.D

Professor of Joint Department of Biomedical Engineering at UNC-Chapel Hill and NC State University

Core Faculty
Phone: 919-966-4959 | Office: 144 MacNider Hall
Email: smgomez@unc.edu | Website: http://gomezlab.bme.unc.edu/

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology, Image Analysis
Research Interests: Systems biology with emphases in cancer and infectious disease

Klaus Hahn, PhD

Distinguished Professor of Pharmacology; Chemical Biology & Medicinal Chemistry

Resource Faculty
Phone: 919-843-2775 | Office: 4043 Genetic Medicine Bldg.
Email: khahn@med.unc.edu | Website: http://www.hahnlab.com

Research Areas: Computational Biophysics, Computational Systems Biology, Image Analysis
Research Interests: visualization and control of protein function in living cells and animals, using protein engineering and small molecule synthesis; signaling dynamics; motility, megakaryocyte and immune cell function

Wesley R Legant, PhD

Joint Assistant Professor of Biomedical Engineering and Pharmacology

Resource Faculty
Phone: (919) 966-4816 | Office: 4047 Genetic Medicine Building
Email: legantw@email.unc.edu | Website: https://www.med.unc.edu/pharm/people/primaryfaculty/wesley-r-legant/wesley-r-legant

Research Areas: Computational Biophysics, Image Analysis
Research Interests: Microscopy, 3D image analysis, biomaterials, cell migration, cancer metastasis, tissue engineering

Yufeng Liu, PhD

Professor of Statistics & Operations Research, Biostatistics, and Genetics

Resource Faculty
Phone: 919-962-4475 | Office: 4250 Genome Science Building
Email: yfliu@email.unc.edu | Website: http://www.unc.edu/~yfliu

Research Areas: Bioinformatics, Image Analysis, Statistical and Populational Genetics
Research Interests: Statistical Machine Learning and Data Mining; High-dimensional Data Analysis; Nonparametric Statistics and Functional Estimation; Bioinformatics; Cancer Genomics; Medical Imaging Data Analysis

Amy Shaub Maddox, PhD

Professor of Biology

Resource Faculty
Phone: 919-843-3228 | Office: 407 Fordham Hall
Email: asm@unc.edu | Website: http://asmlab.web.unc.edu

Research Areas: Computational Biophysics, Image Analysis
Research Interests: Molecular and mechanical mechanisms of cell shape changes in cell division and development

Steve Marron, PhD

Amos Hawley Distinguished Professor of Statistics & Operations Research

Core Faculty
Phone: 919-962-2188 | Office: 352 Hanes Hall
Email: marron@unc.edu | Website: http://marron.web.unc.edu

Research Areas: Bioinformatics, Computational Genomics, Image Analysis
Research Interests: Statistical research on high dimensional, functional, and object oriented data analysis, and data visualization.

Yinglong Miao, PhD

Associate Professor of Pharmacology and Computational Medicine

Core Faculty
Phone: 919-962-5696 | Office: 11004C Mary Ellen Jones Building
Email: yinglong_miao@med.unc.edu | Website: http://miaolab.org/

Research Areas: Bioinformatics, Computational Biophysics, Image Analysis
Research Interests: Dr. Miao develops novel theoretical and computational methods and Deep Learning techniques, which speed up molecular simulations by orders of magnitude, and applies these methods for unprecedented simulations of biomolecular dynamics and cellular signaling events. In collaboration with leading experimentalists, the Miao Lab combines complementary simulations and experiments to uncover functional mechanisms and design drugs of important biomolecules, including G-protein-coupled receptors (GPCRs), membrane-embedded proteases, RNA-binding proteins and RNA.

Jeremy Purvis, PhD

Associate Professor of Genetics

Core Faculty
Phone: 919-962-4923 | Office: 11018C Mary Ellen Jones Building
Email: jeremy_purvis@med.unc.edu | Website: http://genetics.unc.edu/purvislab/

Research Areas: Bioinformatics, Computational Systems Biology, Image Analysis
Research Interests: Our lab uses computational and experimental approaches to study signaling mechanisms in stem cells and cancer pathways. We are especially interested in understanding the molecular mechanisms underlying “irreversible” cell fate decisions such as apoptosis, senescence, and differentiation. We study the timing and mechanism of these decisions using a combination of time-lapse microscopy and computational modeling. Our ultimate goal is to not only understand how cells make decisions under physiological conditions, but to discover how to manipulate these decisions to treat disease.

Pew-Thian Yap, PhD

Professor of Radiology

Core Faculty
Phone: (919) 843-8712 | Office: 3117 Bioinformatics Building
Email: ptyap@med.unc.edu | Website: https://www.yaplab.io/

Research Areas: Image Analysis, Bioinformatics, Computational Biophysics, Computational Systems Biology
Research Interests: Image acquisition, reconstruction, quality control, harmonization, processing, and analysis with application to neuroscience.

Mark Zylka, PhD

Professor of UNC Neuroscience Center, Dept. of Cell Biology & Physiology

Resource Faculty
Phone: 919-966-2540 | Office: 5109 D Neuroscience Research Building
Email: zylka@med.unc.edu | Website: https://www.med.unc.edu/cellbiophysio/faculty/zylka

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology, Image Analysis
Research Interests: Use of genome-wide approaches to study transcriptional regulators linked to autism; Use of RNA-seq and targeted sequencing to identify chemical risk factors for brain disorders (autism, brain aging, neurodegeneration, ADHD); Transcriptional mechanisms associated with long genes