J. Mauro Calabrese, PhD

Assistant Professor of Pharmacology and Lineberger Comprehensive Cancer Center

Resource Faculty
Phone: 919-843-3257 | Office: 4093 Genetic Medicine Bldg.
Email: jmcalabr@med.unc.edu | Website: http://www.med.unc.edu/pharm/calabreselab

Research Areas: Bioinformatics, Comparative Genomics and Molecular Evolution, Computational Genomics
Research Interests: Sequence rules to predict long noncoding RNA function, mechanisms of transcriptional regulation by long noncoding RNAs


Jeff Dangl, PhD

HHMI Investigator and John N. Couch Professor of Biology

Core Faculty
Phone: 919-962-4469 | Office: 4260 Genome Sciences Bldg.
Email: dangl@email.unc.edu | Website: http://labs.bio.unc.edu/dangl/

Research Areas: Comparative Genomics and Molecular Evolution, Computational Genomics, Computational Systems Biology, Statistical and Populational Genetics
Research Interests: Plant Immune System, Plant Microbiome research


Terry Furey, PhD

Associate Professor of Genetics and Biology

Core Faculty
Phone: 919-966-7033 | Office: 5022 Genetic Medicine Bldg.
Email: tsfurey@email.unc.edu | Website: http://fureylab.web.unc.edu/

Research Areas: Computational Genomics, Computational Systems Biology
Research Interests: The Furey Lab is focused on understanding chromatin structure and gene regulation in normal and diseased cells, primarily through the analysis of data from functional high-throughput sequencing experiments.


Shawn Gomez, Eng.Sc.D

Associate Professor of Joint Department of Biomedical Engineering at UNC-Chapel Hill and NC State University

Core Faculty
Phone: 919-966-4959 | Office: 144 MacNider Hall
Email: smgomez@unc.edu | Website: http://gomezlab.bme.unc.edu/

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology, Image Analysis
Research Interests: Systems biology with emphases in cancer and infectious disease


Samir Kelada, PhD, MPH

Assistant Professor of Genetics

Resource Faculty
Phone: 919-962-2148 | Office: 5072 Genetic Medicine Bldg.
Email: samir_kelada@med.unc.edu | Website: https://keladalab.web.unc.edu/

Research Areas: Computational Genomics
Research Interests: genetics and genomics of environmentally-induced airway diseases


Alain Laederach, PhD

Assistant Professor of Biology

Core Faculty
Phone: 919-962-4565 | Office: 3354 Genome Sciences Bldg.
Email: alain@unc.edu | Website: http://ribosnitch.bio.unc.edu/The_Laederach_Lab/Welcome.html

Research Areas: Bioinformatics, Computational Genomics
Research Interests: RNA bioinformatics and transcriptomics


Steve Marron, PhD

Amos Hawley Distinguished Professor of Statistics & Operations Research

Core Faculty
Phone: 919-962-2188 | Office: 352 Hanes Hall
Email: marron@unc.edu | Website: http://marron.web.unc.edu

Research Areas: Bioinformatics, Computational Genomics, Image Analysis
Research Interests: Statistical research on high dimensional, functional, and object oriented data analysis, and data visualization.


Daniel J. McKay, PhD

Assistant Professor of Biology and Genetics

Resource Faculty
Phone: 919-843-2064 | Office: 3358 Genome Sciences Bldg.
Email: dmckay1@email.unc.edu | Website: http://mckaylab.web.unc.edu

Research Areas: Bioinformatics, Computational Genomics
Research Interests: Genetic and epigenetic regulation of gene expression during development


Karen Mohlke, PhD

Professor of Genetics

Resource Faculty
Phone: 919-966-2913 | Office: 5096 Genetic Medicine Bldg.
Email: mohlke@med.unc.edu | Website: http://mohlke.web.unc.edu/

Research Areas: Bioinformatics, Computational Genomics, Statistical and Population Genetics
Research Interests: Genetic basis of complex metabolic traits


Fernando Pardo-Manuel de Villena, PhD

Oliver Smithies Investigator, Professor and Associate Chair of Genetics

Core Faculty
Phone: 919-843-5403 | Office: 5046 Genetic Medicine Bldg.
Email: fernando@med.unc.edu | Website:

Research Areas: Computational Genomics
Research Interests: Our research program lies in the interface between complex traits, evolutionary genetics and computational genomics


Charles M. Perou, PhD

The May Goldman Shaw Distinguished Professor of Molecular Oncology, of Genetics and Pathology & Laboratory Medicine

Core Faculty
Phone: 919-843-5740 | Office: 5111 Marsico Hall
Email: cperou@med.unc.edu | Website: http://peroulab.med.unc.edu/

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: The focus of the Perou Lab is to characterize the biological diversity of human tumors using genomics, genetics, and cell biology, and to then use this information to develop computational predictors of tumor responsiveness and patient outcomes. We use a variety of genomic data types including RNA-seq, DNA exomes/WGS, and DNA copy number data to build these objective models. A major focus of the lab is on novel algorithm development, and the translation of these genomic predictors into clinical assays for use on cancer patients.


Jan F. Prins, PhD

Professor of Computer Science

Core Faculty
Phone: 919-590-6213 | Office: FB334 Brooks Computer Science Building
Email: prins@cs.unc.edu | Website: http://www.cs.unc.edu/~prins/

Research Areas: Bioinformatics, Computational Biophysics, Computational Genomics
Research Interests: RNA sequencing and analysis; Parallel Computing


Praveen Sethupathy, PhD

Assistant Professor of Genetics

Core Faculty
Phone: 919-966-6387 | Office: 5091 Genetic Medicine Bldg.
Email: parveen_sethupathy@med.unc.edu | Website: http://www.med.unc.edu/genetics/sethupathylab/

Research Areas: Bioinformatics, Comparative Genomics and Molecular Evolution, Computational Genomics
Research Interests: Gene regulation; non-coding RNAs; diseases of the liver and intestine including diabetes, lipid disorders, and cancer


Jason Stein, PhD

Assistant Professor of Genetics

Core Faculty
Phone: (919) 843-5541 | Office: 8109C Neuroscience Research Bldg.
Email: jason_stein@med.unc.edu | Website: http://www.steinlab.org/

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: The focus of our research is finding and modeling genetic variants influencing human brain structure and function.


William Valdar, PhD

Associate Professor of Genetics

Core Faculty
Phone: 919-843-2833 | Office: 5113 Genetic Medicine Bldg.
Email: william.valdar@unc.edu | Website: http://valdarlab.unc.edu

Research Areas: Computational Genomics, Statistical and Populational Genetics
Research Interests: Quantitative and statistical genetics: modeling the relationship between genes and complex disease in model organisms and humans.


Benjamin Vincent, MD

Assistant Professor of Medicine, Division of Hematology/Oncology

Resource Faculty
Phone: 919-962-8412 | Office: 5206 Marsico Hall
Email: bgvincen@unch.unc.edu | Website:

Research Areas: Computational Immunology, Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: Current research focuses on how immunogenomics features including T cell receptor and B cell receptor repertoire characteristics predict survival and response to immunotherapy in breast cancer, bladder cancer, and acute myeloid leukemia.


Todd Vision, PhD

Associate Professor of Biology and Adjunct Associate Professor of School of Information and Library Science

Core Faculty
Phone: 919-962-4479 | Office: 3155 Genome Sciences Bldg.
Email: tjv@bio.unc.edu | Website: https://visionlab.web.unc.edu/

Research Areas: Bioinformatics, Comparative Genomics and Molecular Evolution, Computational Genomics, Statistical and Populational Genetics
Research Interests: I am interested in computational, statistical and quantitative approaches to testing ideas about the processes governing the evolution of genetic systems, from changes in gene content to major morphological innovations and other complex traits.


Kevin M. Weeks, PhD

Kenan Distinguished Professor of Chemistry

Resource Faculty
Phone: 919-962-7486 | Office: 3258 Genome Sciences Building
Email: weeks@unc.edu | Website: http://www.chem.unc.edu/rna/

Research Areas: Bioinformatics, Computational Biophysics, Computational Genomics
Research Interests: Chemical Biology, Structural Biology, and Bioinformatics of the Transcriptome


Kirk Wilhelmsen, PhD

Professor of Genetics

Core Faculty
Phone: 919-966-1373 | Office: 5093 Genetic Medicine Bldg.
Email: kirk_wilhelmsen@med.unc.edu | Website: http://kirkwilhelmsen.web.unc.edu/

Research Areas: Bioinformatics; Comparative Genomics & Molecular Evolution; Computational Genomics; Statistical & Population Genetics
Research Interests: Dr Wilhelmsen leads a lab group in the Dept. of Genetics and a Computational Group at RENCI (www.renci.org). The labs groups effort in human genetics is focused on behavior and neurodegeneration by annotation of the human genome using data intensive strategies. The lab group has developed several new analytic techniques. The lab is intensively engaged in the development of molecular techniques to study epigenetic phenomena and gene expression in complex populations of cells. The RENCI bioinformatics groups provide data intensive informatics approaches to support multidisciplinary research projects at the three triangle campuses. The current focus of this activity is to support genomics research. The group develops and maintains pipelines to support medical genomics analysis.


Di Wu, PhD

Assistant Professor of Periodontics, School of Dentistry; Biostatistics

Resource Faculty
Phone: 919-537-3277 | Office: 4504 Koury Oral Health Sciences Building
Email: dwu@unc.edu | Website: http://sph.unc.edu/adv_profile/di-wu-phd/

Research Areas: Bioinformatics, Computational Genomics, Computational System Biology, Statistical and Population Genetics​
Research Interests: Development of statistical methods for multidimensional genomic data integration to understand the biological mechanism of diseases.


Mark Zylka, PhD

Associate Professor of UNC Neuroscience Center, Dept. of Cell Biology & Physiology

Resource Faculty
Phone: 919-966-2540 | Office: 5109 D Neuroscience Research Building
Email: zylka@med.unc.edu | Website: https://www.med.unc.edu/cellbiophysio/faculty/zylka

Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology, Image Analysis
Research Interests: Use of genome-wide approaches to study transcriptional regulators linked to autism; Use of RNA-seq and targeted sequencing to identify chemical risk factors for brain disorders (autism, brain aging, neurodegeneration, ADHD); Transcriptional mechanisms associated with long genes