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Congratulations to Dan Oreper and Yanwei Cai (Valdar Lab) for their recent paper in G3 Journal titled “Inbred Strain Variant Database (ISVdb): A repository for probabilistically informed sequence differences among the Collaborative Cross strains and their founders.” The manuscript describes the development of a database [] for genetics researchers using the Collaborative Cross (CC) and other inbred mouse strains. Rather than merely holding data, the database software uses a series of probabilistic calculations to several sources of data at once — on genotypes, haplotypes and sequencing-based variant annotation – to give probabilistic predictions of both the state and functional consequences of sequence variants present across the genomes of CC and derived populations. Dan and Yanwei’s publication may be read at

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