Alain Laederach, PhD
Alain Laederach, PhD
Professor of
Biology
Core Faculty
Phone: 919-962-4565 | Office: 3354 Genome Sciences Bldg.
Email: alain@unc.edu | Website: http://ribosnitch.bio.unc.edu/The_Laederach_Lab/Welcome.html
Research Areas: Bioinformatics, Computational Genomics
Research Interests: RNA bioinformatics and transcriptomics
Karen Mohlke, PhD
Karen Mohlke, PhD
Professor of
Genetics
Resource Faculty
Phone: 919-966-2913 | Office: 5096 Genetic Medicine Bldg.
Email: mohlke@med.unc.edu | Website: http://mohlke.web.unc.edu/
Research Areas: Bioinformatics, Computational Genomics, Statistical and Population Genetics
Research Interests: Genetic basis of complex metabolic traits
Jeremy Purvis, PhD
Jeremy Purvis, PhD
Professor and Associate Chair for Education of
Genetics
Core Faculty
Phone: 919-962-4923 | Office: 11018C Mary Ellen Jones Building
Email: jeremy_purvis@med.unc.edu | Website: http://genetics.unc.edu/purvislab/
Research Areas: Bioinformatics, Computational Systems Biology, Image Analysis
Research Interests: Our lab uses computational and experimental approaches to study signaling mechanisms in stem cells and cancer pathways. We are especially interested in understanding the molecular mechanisms underlying “irreversible” cell fate decisions such as apoptosis, senescence, and differentiation. We study the timing and mechanism of these decisions using a combination of time-lapse microscopy and computational modeling. Our ultimate goal is to not only understand how cells make decisions under physiological conditions, but to discover how to manipulate these decisions to treat disease.
Brian Kuhlman, PhD
Brian Kuhlman, PhD
Professor of
Biochemistry & Biophysics
Core Faculty
Phone: 919-843-0188 | Office: 3096 Genetic Medicine Bldg.
Email: bkuhlman@email.unc.edu | Website: https://sites.google.com/site/kuhlmanlabwebpage/
Research Areas:
Research Interests: Protein Engineering and Design
Klaus Hahn, PhD
Klaus Hahn, PhD
Distinguished Professor of
Pharmacology; Chemical Biology & Medicinal Chemistry
Resource Faculty
Phone: 919-843-2775 | Office: 4043 Genetic Medicine Bldg.
Email: khahn@med.unc.edu | Website: http://www.hahnlab.com
Research Areas: Computational Biophysics, Computational Systems Biology, Image Analysis
Research Interests: visualization and control of protein function in living cells and animals, using protein engineering and small molecule synthesis; signaling dynamics; motility, megakaryocyte and immune cell function
Terry Furey, PhD
Terry Furey, PhD
Professor of
Genetics and Biology
Core Faculty
Phone: 919-966-7033 | Office: 5022 Genetic Medicine Bldg.
Email: tsfurey@email.unc.edu | Website: http://fureylab.web.unc.edu/
Research Areas: Computational Genomics, Computational Systems Biology
Research Interests: The Furey Lab is focused on understanding chromatin structure and gene regulation in normal and diseased cells, primarily through the analysis of data from functional high-throughput sequencing experiments.
J. Mauro Calabrese, PhD
J. Mauro Calabrese, PhD
Associate Professor of
Pharmacology and Lineberger Comprehensive Cancer Center
Resource Faculty
Phone: 919-843-3257 | Office: 4093 Genetic Medicine Building
Email: jmcalabr@med.unc.edu | Website: http://www.med.unc.edu/pharm/calabreselab
Research Areas: Bioinformatics, Comparative Genomics and Molecular Evolution, Computational Genomics
Research Interests: Sequence rules to predict long noncoding RNA function, mechanisms of transcriptional regulation by long noncoding RNAs
Alex Tropsha, PhD
Alex Tropsha, PhD
K.H. Lee Distinguished Professor of
Chemical Biology & Medicinal Chemistry
Core Faculty
Phone: 919-966-2955 | Office: 100K Beard Hall
Email: alex_tropsha@unc.edu | Website: https://pharmacy.unc.edu/Directory/tropsha
Research Areas:
Research Interests: Computational drug discovery; Cheminformatics; Computational geometry of protein structure
Samir Kelada, PhD, MPH
Samir Kelada, PhD, MPH
Associate Professor of
Genetics
Resource Faculty
Phone: 919-962-2148 | Office: 5072 Genetic Medicine Building
Email: samir_kelada@med.unc.edu | Website: https://keladalab.web.unc.edu/
Research Areas: Computational Genomics
Research Interests: genetics and genomics of environmentally-induced airway diseases
Timothy Elston, PhD
Timothy Elston, PhD
Professor of
Pharmacology
Core Faculty
Phone: 919-843-7670 | Office: 4092 Genetic Medicine Bldg.
Email: telston@med.unc.edu | Website: http://www.med.unc.edu/pharm/elstonlab/
Research Areas: Computational Biophysics, Computational Systems Biology, Image Analysis
Research Interests: Mathematical modeling of signaling pathways and regulatory networks