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Faculty Members

Yun Li, PhD

June 25, 2015

Yun Li, PhD

Professor of Genetics and Biostatistics

Core Faculty
Phone: 919-843-2832 | Office: 5043 Genetic Medicine Building
Email: yunli@med.unc.edu | Website: https://yunliweb.its.unc.edu

Research Areas: Bioinformatics, Statistical and Populational Genetics
Research Interests: The focus of my research is on the development of statistical methods and their application to the genetic dissection of complex diseases and traits.

Karen Mohlke, PhD

June 25, 2015

Karen Mohlke, PhD

Professor of Genetics

Resource Faculty
Phone: 919-966-2913 | Office: 5096 Genetic Medicine Bldg.
Email: mohlke@med.unc.edu | Website: http://mohlke.web.unc.edu/

Research Areas: Bioinformatics, Computational Genomics, Statistical and Population Genetics
Research Interests: Genetic basis of complex metabolic traits

Jeremy Purvis, PhD

June 25, 2015

Jeremy Purvis, PhD

Associate Professor of Genetics

Core Faculty
Phone: 919-962-4923 | Office: 11018C Mary Ellen Jones Building
Email: jeremy_purvis@med.unc.edu | Website: http://genetics.unc.edu/purvislab/

Research Areas: Bioinformatics, Computational Systems Biology, Image Analysis
Research Interests: Our lab uses computational and experimental approaches to study signaling mechanisms in stem cells and cancer pathways. We are especially interested in understanding the molecular mechanisms underlying “irreversible” cell fate decisions such as apoptosis, senescence, and differentiation. We study the timing and mechanism of these decisions using a combination of time-lapse microscopy and computational modeling. Our ultimate goal is to not only understand how cells make decisions under physiological conditions, but to discover how to manipulate these decisions to treat disease.

Kevin M. Weeks, PhD

June 25, 2015

Kevin M. Weeks, PhD

Kenan Distinguished Professor of Chemistry

Resource Faculty
Phone: 919-962-7486 | Office: 3258 Genome Sciences Building
Email: weeks@unc.edu | Website: http://www.chem.unc.edu/rna/

Research Areas: Bioinformatics, Computational Biophysics, Computational Genomics
Research Interests: Chemical Biology, Structural Biology, and Bioinformatics of the Transcriptome

Klaus Hahn, PhD

June 25, 2015

Klaus Hahn, PhD

Distinguished Professor of Pharmacology; Chemical Biology & Medicinal Chemistry

Resource Faculty
Phone: 919-843-2775 | Office: 4043 Genetic Medicine Bldg.
Email: khahn@med.unc.edu | Website: http://www.hahnlab.com

Research Areas: Computational Biophysics, Computational Systems Biology, Image Analysis
Research Interests: visualization and control of protein function in living cells and animals, using protein engineering and small molecule synthesis; signaling dynamics; motility, megakaryocyte and immune cell function

Terry Furey, PhD

June 25, 2015

Terry Furey, PhD

Professor of Genetics and Biology

Core Faculty
Phone: 919-966-7033 | Office: 5022 Genetic Medicine Bldg.
Email: tsfurey@email.unc.edu | Website: http://fureylab.web.unc.edu/

Research Areas: Computational Genomics, Computational Systems Biology
Research Interests: The Furey Lab is focused on understanding chromatin structure and gene regulation in normal and diseased cells, primarily through the analysis of data from functional high-throughput sequencing experiments.

J. Mauro Calabrese, PhD

June 25, 2015

J. Mauro Calabrese, PhD

Associate Professor of Pharmacology and Lineberger Comprehensive Cancer Center

Resource Faculty
Phone: 919-843-3257 | Office: 4093 Genetic Medicine Building
Email: jmcalabr@med.unc.edu | Website: http://www.med.unc.edu/pharm/calabreselab

Research Areas: Bioinformatics, Comparative Genomics and Molecular Evolution, Computational Genomics
Research Interests: Sequence rules to predict long noncoding RNA function, mechanisms of transcriptional regulation by long noncoding RNAs