Alexander Rubinsteyn, PhD
Alexander Rubinsteyn, PhD
Assistant Professor of
Genetics
Core Faculty
Phone: TBA | Office: 11202B Mary Ellen Jones Building
Email: alex.rubinsteyn@unc.edu | Website: https://rubinsteyn.web.unc.edu/
Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: Machine learning for adaptive immunity, immunogenomics, and rapid vaccine design targeting cancer neoantigens and emerging pathogens.
Christoph Rau
Christoph Rau, PhD
Assistant Professor of
Genetics & Computational Medicine
Core Faculty
Phone: 919-962-5641 | Office: 11004B Mary Ellen Jones Building
Email: ChristophRau@unc.edu | Website: https://raulab.web.unc.edu/
Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology, Statistical and Population Genetics
Research Interests: The Rau lab utilizes populations of mice to study the transcriptomic and epigenomic landscape underlying cardiovascular disorders using a combination of wet and dry-lab techniques.
Adam Palmer, PhD
Adam Palmer, PhD
Assistant Professor of
Pharmacology
Core Faculty
Phone: (919) 962-5967 | Office: 11-202A Mary Ellen Jones Building
Email: palmer@unc.edu | Website: http://www.med.unc.edu/pharm/directory/adam-palmer-phd/
Research Areas: Bioinformatics and Computational Systems Biology.
Research Interests: We investigate and develop combinations of cancer therapies using experiments, simulations, and computational analysis of clinical data.
Jesse Raab, PhD
Jesse Raab, PhD
Assistant Professor of
Genetics
Resource Faculty
Phone: (919) 843-6475 | Office: Genetic Medicine Building
Email: jraab@med.unc.edu | Website: http://raablab.web.unc.edu/
Research Areas: Bioinformatics, Computational Genomics, and Computational Systems Biology.
Research Interests: Regulation and function of altered chromatin remodeling complex activity.
Anthony Zannas, MD, MSc, PhD
Anthony Zannas, MD, MSc, PhD
Associate Professor of
Psychiatry and Genetics
Core Faculty
Phone: 919-962-4918 | Office: 438 Taylor Hall
Email: anthony_zannas@med.unc.edu | Website: http://www.zannaslab.org/
Research Areas: Bioinformatics, Computational Genomics, Computation Systems Biology.
Research Interests: Our lab seeks to uncover the epigenetic mechanisms linking psychosocial stress with disease risk.
Daniel Dominguez, PhD
Daniel Dominguez, PhD
Assistant Professor of
Pharmacology
Core Faculty
Phone: (919) 966-0131 | Office: 4113 Genetic Medicine Building
Email: didoming@email.unc.edu | Website: https://dominguez-lab.org/
Research Areas: Bioinformatics, Comparative Genomics and Molecular Evolution, Computational Genomics, Computational Systems Biology
Research Interests: The Dominguez lab studies how gene expression is controlled by proteins that bind RNA. We apply high-throughput biochemical and computational approaches to understand protein-RNA interactions, RNA processing, and gene regulation in normal and disease biology.
Shehzad Sheikh, MD, PhD
Shehzad Sheikh, MD, PhD
Associate Professor of
Genetics and Medicine
Resource Faculty
Phone: (919) 966-0745 | Office: 7320 Medical Biomolecular Research Building
Email: sheisx@med.unc.edu | Website: http://sheikhlab.web.unc.edu/
Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: We seek to understand how information is encoded and dynamically utilized in immune cells from healthy and disease prone intestines (Crohn’s disease and Ulcerative colitis). We focus specifically on genes that regulate response to the bacteria that normally reside in our intestines. We use genome-sequencing technology to precisely identify regions throughout the genome that are potential ‘on’ or ‘off’ switches for these genes.
Katherine A. Hoadley, PhD
Katherine Hoadley, PhD
Associate Professor of
Genetics
Core Faculty
Phone: (919) 962-8416 | Office: 11-212 Mary Ellen Jones Building
Email: hoadley@med.unc.edu | Website: https://unclineberger.org/people/profiles/katherine-hoadley
Research Areas: Computational Genomics, Bioinformatics, Computational Systems Biology
Research Interests: My research interest is in genomic characterization and integrative genomic approaches to better understand cancer. My group is part of the NCI Genome Data Analysis Center focused on RNA expression analysis. We have a number of ongoing projects including developing molecular classifications for potential clinical utility, developing methods for deconvolution to understand bulk tissue heterogeneity, analysis of driver negative cancers, and analysis of ancestry markers with cancer features.
Doug Phanstiel, PhD
Doug Phanstiel, PhD
Assistant Professor of
Cell Biology & Physiology
Core Faculty
Phone: 919-843-8847 | Office: 4019 Thurston Bowles Building
Email: douglas_phanstiel@med.unc.edu | Website: http://www.unc.edu/~dphansti/
Research Areas: Bioinformatics, Computational Genomics, Computational Systems Biology
Research Interests: We employ experimental and computational approaches to study the mechanisms through which enhancers and three-dimensional chromatin structure regulate gene transcription during cellular differentiation. The goals of our computational work include improved detection and quantification of three-dimensional chromatin structures and new tools for visualizing multi-dimensional genomic data.
Di Wu
Di Wu, PhD
Associate Professor of
Periodontics, School of Dentistry; Biostatistics
Core Faculty
Phone: 919-537-3277 | Office: 4504 Koury Oral Health Sciences Building
Email: dwu@unc.edu | Website: http://sph.unc.edu/adv_profile/di-wu-phd/
Research Areas: Bioinformatics, Computational Genomics, Computational System Biology, Statistical and Population Genetics
Research Interests: Development of statistical methods for multidimensional genomic data integration to understand the biological mechanism of diseases.